10.5.23-Showcase-Tokyo-Metanovas_Biotech

[SPEAKING JAPANESE]

LUN YU: You can also call me Lun Yu. I'm the co-founder and CTO of Matanovas Biotech. I got my PhD degree six years ago from MIT. Now I'm leading our California based team in leveraging AI and knowledge graph to develop clinical grade consumer health products.

When you walk down the aisle of a beauty store or supplement store you are met with countless products. But you may notice a glaring issue. Many of the products don't stand out from each other. And more concerning, many don't have proven clinical benefits.

At Matanovas we're changing that. We believe there are three things we need to focus on. First, we need to deeply understand human biology for informed product development. Second, we need to identify and design ingredients that are not only potent, but also safe for long term use. And lastly, we need to adopt a systematic approach to solve complex biological problems for true innovations.

So to tackle this we have built four integrated platforms at Matanovas. I will walk you through them one by one. MetaNLP scans millions of scientific documents, converting vast human knowledge into digestible and accessible data. With such data we can navigate specific biological domains easily.

And MataKG, our ultralarge biomedical knowledge graph enables us to infer and visualize biological interactions driving novel discoveries and innovative product development. With MetaOmics, we harness multi-omics data for targeted precision product development, tailored for specific demographics.

And last, we have MetaPep, which merges deep learning and molecular simulations for peptide design. It rapidly designs bioactive peptides with impressive success rates. And while individual platforms might be found elsewhere, we are pioneers in integrating all of them for a holistic end to end development.

So our platforms have been extensively used in biological understanding, ingredient discovery and design, and product development. The unique value we offer to our clients includes identifying better product strategies from novel biological insights, improving clinical efficacy for our novel peptides and ingredient combinations, unique product offerings and brand positioning from precision product development, and science driven marketing and storytellings by assembling various kinds of scientific evidence.

Our current clients range from pharmaceutical companies, established consumer brands, and emerging consumer brands, both globally and locally, as listed here. Next, let me demonstrate two success stories at Matanovas using our technologies. Leveraging our MetaKG platform we launched the world's first AI designed skincare solutions for vascular type under-eye dark circle, which is prevalent in Asian women.

We began the process by identifying the key biological processes behind this issue. And then we navigate the knowledge graph to predict the novel natural products targeting the underlying genes. So from the platform's recommendations, our formulation scientists formulated the final product. A third party trial confirmed this efficacy with 93% of the users noting a reduced pigmentation in just 14 days.

And through our MetaPep platform we crafted unique bioactive peptides with dual benefits, antimicrobial, and anti-inflammatory properties. It targets the TLR2 proteins, curbing the nitride oxide productions, and also pro-inflammatory cytokine release during skin inflammation.

It also combats the C. acne, which is the primary acne culprit. Also, a third party trial-- I think this is kind of outdated. A third party trial also verified its power, showing reduced acne spots in just seven days, with 90% of the users witnessing acne improvement.

I believe our stories have demonstrated our expertise and strength. Now we invite you to work with us. In Asia we have unique business focuses. We focus on Asian ingredients, especially mining the hidden gems in Chinese, Japanese, and Korean traditional medicines, and combine them with the novel peptides for enhanced efficacy. We appreciate our Asian distinction and are passionate about developing unique products for Asian consumers.

Since our foundations we have worked with numerous Asian brands, from established to emerging. We would like to leverage our experience and insights from them to serve our Japanese clients. And we take pride in Asian innovations, and we love to bring them to the world. That's why we also have clients with a global presence to help us transcend the national boundaries.

We offer three types of services, first, technical solutions, where we offer technical consulting for biological discoveries, ingredient selections, and product development. We also work with our clients to co-develop novel and new ingredients or products. And we'll take royalty shares from the final sales.

If you're just looking for a unique ingredient, we also offer direct ingredient sales to meet your product requirements. No matter you are a pharmaceutical company, cosmeceutical company, or nutraceutical companies, we look forward to bringing tangible values to your product innovations.

We're Matanovas. Your next breakthrough will start with us.

[SPEAKING JAPANESE]

[APPLAUSE]