10.10.23-Showcase-Seoul-Metanovas_Biotech

LUN YU: [NON-ENGLISH SPEECH] This is Lun Yu. I'm the co-founder and CTO of Metanovas Biotech. I got my PhD from MIT six years ago. Now I'm leading our California-based team in leveraging AI and knowledge graph to develop clinical grade consumer health products.

When you walk down the aisle of a beauty store or a supplement store, you are met with countless products. But you may notice a glaring issue. Many of the products don't stand out from each other, and more concerning, many don't have proven clinical benefits. At Metanovas, we're changing that.

We believe there are three things we need to focus on. First, we need to deeply understand human biology for informed product development. Second, we need to identify and design ingredients that are not only potent but also safe for long-term use. And lastly, we need to adopt a systematic approach to solve complex biological problems for true innovations.

At Metanovas, we have built four integrated platforms to tackle this. I will walk you through them one by one. MetaNLP scans millions of scientific documents, converting vast human knowledge into digestible and accessible data. With such data, we can navigate specific biological domains very easily. MetaKG, our ultralarge biomedical knowledge graph, enables us to infer and visualize biological interactions driving novel discovery and innovative product development.

With MetaOmics we harness multi-omics data for targeted precision product development tailored for specific demographics. And lastly, MetaPep merges deep learning and molecular simulations peptide design. It rapidly designs bioactive peptides with impressive success rates.

While individual platform might be found elsewhere, we are pioneers in integrating all of them for holistic end-to-end development. Our platforms have been extensively used in biological understanding, ingredient design and discovery, and product development. The unique value we offer to our clients include identifying better product strategy from novel biological insights, proven clinical efficacy from novel peptides and ingredient combinations, unique product offerings and brand positioning by precision product development, and science-driven marketing storytelling by assembling various kinds of scientific evidence.

Our current clients include a pharmaceutical company, established consumer brands, and emerging consumer brands, both globally and locally, as listed here. Now, let me demonstrate two success stories at Metanovas using our technology. Leveraging our MetaKG platform, we launched the world's first AI-designed skincare solutions for vascular-type under-eye dark circle.

We began the process by pinpointing key biological processes behind this issue, and then we navigate the knowledge graph to predict novel natural products targeting the underlying genes. From the platform's recommendations, our formulation scientists formulated the final product. And the third party trial verified its efficacy, with 93% of users noting reduced pigmentation in just 14 days.

Through MetaPep platform, we crafted unique peptides with dual benefits, antimicrobial and anti-inflammatory properties. It targets the TLR2 protein, curbing nitric oxide production and pro-inflammatory cytokine release during the skin inflammation. It also combats the C acne bacteria, which is the primary acne culprit. A third party trial also verified its power, showing reduced acne spots in just seven days, with 90% of the users witnessing acne improvements.

I believe our success stories have demonstrated our expertise and strength. Now we will invite you to work with us. In Asia, we have unique business focuses. We focus on Asian ingredients, especially mining the hidden gems in Asian traditional medicine, and combine them with bioactive peptides for enhanced efficacy.

We appreciate our Asian distinction, are passionate about developing unique products for Asian consumers. Since our foundation, we have worked with numerous Asian brands, from established to emerging. We would like to leverage our insights and experience from them to help serve our Korean clients.

We take pride in Asian innovations and would love to bring them to the world. That's why we also work with clients with global presence, to help us transcend the national boundaries. We offer three types of services, technical solution, where we offer technical consulting for biological discovery, ingredient selection, and product development.

We also work with our client to co-develop novel ingredients or products, and we take a royalty share from the final sales. If you're just looking for a unique ingredient, we also offer direct ingredient sales to meet your product requirements. No matter you are a pharma company, cosmeceutical company, or nutraceutical company, we look forward to bringing tangible values to your product innovations. We're Metanovas. Your next breakthrough will start with us. [NON-ENGLISH SPEECH]

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